Activation of the Human Ah Receptor by Aza-Polycyclic Aromatic Hydrocarbons and Their Halogenated Derivatives.
نویسندگان
چکیده
منابع مشابه
Activation of the human Ah receptor by aza-polycyclic aromatic hydrocarbons and their halogenated derivatives.
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor through which dioxins and carcinogenic polycyclic aromatic hydrocarbons cause altered gene expression and toxicity. Ten aza-polycyclic aromatic hydrocarbons (aza-PAHs), consisting of nitrogen substituted naphthalenes, phenanthrenes, chrysenes, and benzo[a]pyrenes (BaPs), were subjected to analysis of their structure-acti...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2003
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.26.448